COMPREHENSIVE EVALUATION OF BIOMEDICAL PRODUCTS IN RESEARCH BASED ON ENTROPY WEIGHT TOPSIS MODEL
Li Tiezhu, Ge Yan,Wu Jie,Tang Jun,Li Yu,Zhu Rong
Key words: entropy weight TOPSIS; correlation; comprehensive evaluation.
Abstract
According to the characteristic data characteristics of biopharmaceutical products under research, standardized processing is carried out to evaluate the products from the macro level, and 7 indicators in three categories of application for registration
(application stage, application type, registration classification), highest progress (domestic highest progress of the product, global highest progress of common name, domestic highest progress of common name), and application number of products of the same variety are selected as the evaluation criteria. The correlation between evaluation indexes was analyzed, and the entropy weight TOPSIS model was constructed to
evaluate the products under research. The results showed that all indexes met the evaluation correlation requirements, and there was a significant negative correlation between the application for registration and the highest progress, while there was no correlation between the number of applications for the same product and the application for registration and the highest progress. The weight of application type, global highest progress of generic name, and domestic highest progress of generic name is higher, indicating that the research products focus on new drugs and clinical aspects, while the weight of application stage, registration classification, and domestic highest progress of products is lower, indicating that the difference between the research products in these three aspects is not high. This also requires us to provide certain guidance in the subsequent development of evaluation indicators. The evaluation ranking represents the advantages and disadvantages of each product under research, which helps to guide the improvement direction of the drug under research and provide guarantee for better access to the hands of patients in the future