ASSESSMENT OF THE PLASMA LIPID SYSTEM ADAPTIVE STRATEGIES BY DIFFERENTIAL ENTROPY MODELING USE
Chonkoeva A.A., Mukhamedova I.P.
Introduction. The lipid system of the blood is an example of a dynamic, open thermodynamic, stochastic system, which includes the following components: lipoproteins containing triacylglycerides, cholesterol and cholesterol esters, the state of which can be described by an entropy value and thus characterize the state of the like system as a whole.
The aim of the study is to consider the possibility of using differential-entropy mathematical modeling for stationary and dynamic adaptation of the lipid system and its components, as well as for the diagnosis of stressed and disadaptive states.
Materials and methods. There were 18 journal articles in Russian and 3 journal articles in English published at earliest in 2004; 3 dissertations, 10 national statistical sources and profiles, and 5 books were reviewed to present in the article.
Results. The study involved 120 students of medical universities in Kyrgyzstan (60 local and 60 foreign students). The control group was the indicators of the general population of healthy people of the corresponding age and gender. We selected the following laboratory-determined parameters of the lipid system for analysis - triacylglycerides (TG), high-density lipoproteins (HDL), total cholesterol (TC), while we excluded low-density lipoproteins (LDL) from the analysis, because it is determined by the calculation method according to the Friedwald’s formula based on the indicators of TC, TG and HDL. We used the techniques of entropy mathematical modeling presented in the O.M. Gerget’s (2011) and O.G. Berestneva (2014) study to assess the individual adaptation strategy of the students' lipid system. Integral criteria were used to calculate the degree of deviation of TG, TC and HDL values from the normal (from the value of the mathematical expectation of the reference (control) group and the permissible standard deviation).
Conclusions. An algorithm for lipid system adaptive strategies identification is given for diagnosing of four major adaptive behavior states: adaptive (normal), compensated (slightly tense), decompensated (tense) and disadaptive (overtense). Comparative analysis of identified strategies showed that adaptive behavior of lipid system and its components of foreign students are tenser than native student’s lipid system behavior. Analysis did not confirm ethnic specificity in adaptive strategies of lipid system as a whole, but confirm thin differences between male and female lipid system components adaptive response in both ethnic groups. The data confirm that physiological mechanisms of plasma lipid system rearrangement are common for different ethnic, but specific for sexual groups.
Key words: differential entropy, adaptation, plasma lipoproteins, foreign students.
ECHINOCOCCOSIS OF THE PERICARDIUM (CASE FROM PRACTICE)
I.H. Bebezov, A.A. Rakimbaev, M.K. Dzhundubaev, D.B. Toktosunova, E.D. Seitahunova, R.S. Kalieva, A.K. Turgunov
Echinococcosis is a parasitic disease widespread in many countries of the world and continues to remain a serious medical and national economic problem. The article presents a rare case of a giant echinococcal cyst localized in the pericardial cavity with invasion into the left ventricular myocardium and causing compression of the left heart, as well as surgical intervention aimed at its complete removal.
Key words: echinococcosis of the pericardium, echocardiography, computed tomography.
POSSIBILITIES OF SURGICAL APPROACHES TO REMOVE TUMORS OF THE PARANASAL SINUSES THAT HAVE SPREAD TO THE BASE OF THE SKULL
A.M. Orozalieva, B.D. Shalabaev, Ali Zeshan, Zeeshan Majeed
Introduction. Surgical treatment of tumors of the paranasal sinuses that have spread to the base of the skull, include those with invasion into the cranial fossa, belonging to a severe and often dangerous category and fraught with serious complications. Therefore, the choice of a surgical approach to remove such tumors is of particular importance.
The aim. To make a comparative analysis of the possibilities of surgical approaches for lateral rhinotomy with continuation to the frontal sinuses, extended rhinotomy, and Lauers-Balon in developing an optimal treatment for various variants of the spread of tumors at the base of the skull.
Materials and methods. To determine the extent of the tumor and justify the choice of surgical access, an examination was carried out using computed tomography according to the methods described in the literature.
We considered clinical material, including the results of surgical treatment of 41 patients with tumors and tumor-like diseases of the maxillofacial region with spread to the structures of the base of the skull.
Results. Among the 41 patients selected T-shaped approach and extended lateral rhinotomy were done. In patients with tumors present in the frontal sinus and ethmoid labyrinth with extensions to anterior cranial fossa T-shaped approach showed a good results, while 32 cases with tumor of jaw the procedure of extended lateral rhinotomy showed good visual access and good results.
Conclusions. The conclusion of this work is that for the removal of the cancer or masses from the ethmoid labyrinth and frontal sinuses with extension to the anterior cranial fossa the T-shaped approach combine with shortened
lateral rhinotomy can be performed. Extended lateral rhinomaxillotomy can be the option for the removal of cancers of upper jaw and paramaxillary formations with invasion into the basal of skull.
For the prevention of meningocerebral completion in dura matter defect our method of plastic closer of dural defect is commendable.
Key words: tumors of the paranasal sinuses with extension to the base of the skull, surgical treatment of tumors of the base of the skull.
HISTOSTRUCTURE OF INTRAMURAL LYMPHOID FORMATIONS OF THE HEART
Masalbek A. Satybaldiev, Aida M. Ergesheva, Adelya E. Seytkulova
The system intraorganic Structures I lymphatic collectors of the heart, their size, structure and location in time of personal areas of wall lymphangions . Generation and configuration of muscle fibers in the structure of the uniting vessel. A diagram of the connection of various structures of the lymphatic system for the implementation of the passage of lymph, from the subendocardial lymphatic capillaries to the main vessels of the outflow.
Key words: lymphangion, lymphatic bed, collector, caliber, shape.
CLINICAL CASE RARE COMBINATIONS PRIMARY HYPERPARATHYROIDISM WITH DEFICIENCY OF VITAMIN D
Sultanalieva R.B., Knyazeva V.G., Kudaibergenova N.T.
Primary hyperparathyroidism is a rare but interesting pathology that affects not only the parathyroid glands, but also bones, kidneys, and other organs. This pathology is rarely diagnosed at an early stage. We have given an example of an unusual combination of primary hyperparathyroidism and vitamin D deficiency.
Key words: Parathyroid gland, vitamin D, hormones, calcium.
THE EFFECTIVENESS OF COMPLEX THERAPY FOR THE REGENERATION OF POSTOPERATIVE WOUNDS (EXPERIMENTAL STUDY)
Summary: The study was carried out on 60 white Wistar rats, simulating a surgical wound. The rats were divided into 5 groups of 10 rats each. Group 1 is control - rats from this group were made an incision on the sidewall, abdominal wall, followed by natural healing within 10 days; Group 2 - an incision followed by the use of chitosan ointment; Group 3 - the wound was exposed to photostimulation treated with methylene blue; Group 4 - physical activity in the postoperative period on a treadmill for 30 minutes; Group 5 - complex application of chitosan, photostimulation, and physical activity. Wound healing was recorded by determining the area, photo-fixation of the wound, and histological examinations of the skin and internal organs were performed.
Outcomes obtained: The best wound healing according to planimetry and histological studies was significant observed in group 5 with the complex treatment of the surgical wound.
Conclusions: The rehabilitation complex for large surgical wounds should include previously local effects of physiotherapeutic procedures and physical activity.
Key words: surgical wound, rehabilitation, photomodulation, and physical exercises.
DEVELOPMENT OF A METHOD FOR ENDOSCOPIC RECANALIZATION OF THE URETHRA
Faizulla Yu. Yuldashev, Furkat R. Nasirov, Jalal Kh. Mirkhamidov, Safojon S. Kasimov, Muhammadzarif K. Bakhadirkhanov, Nozima J. Uralova
The article summarizes the results of the analysis of data from the treatment of 53 atients who underwent endoscopic recanalization of obliterated urethra, followed by electric esection scar tissue. Conducted cl inical studies have shown that recurrences, after the ntervention, by the end of 1 year of observation, occur in 18.9% of patients.
Key words: obliteration of the urethra, endoscopic treatment, efficacy.