Eurasian Medical Journal

International Higher School of Medicine

ISSN 1694-8254

STATE OF IMMUNE REACTIVITY IN EXPERIMENTAL ANIMALS WITH CARCINOSARCOMA WALKER 256 EXPOSED TO GENERAL HYPERTHERMIA

E.A. Vaskina1, O.Zh. Uzakov2, A.V. Efremov1

Abstract
The paper presents immunity indicators in rats with Walker 256 carcinosarcoma during the development of the tumor process and exposure to general hyperthermia. The data obtained indicate that the effect of general hyperthermia on the body of experimental animals with Walker 256 carcinosarcoma is accompanied by multidirectional changes in the parameters of the immune system both in the direction of their decrease and increase in various periods after hyperthermia. This may be due to the activation of endogenous regulatory systems that determine the body's immune reactivity.
Keywords: Walker 256 carcinosarcoma, humoral and cellular immunity, general hyperthermia.