Eurasian Medical Journal

International Higher School of Medicine

ISSN 1694-8254

INFLUENCE OF GREEN TOBACCO ON CHILD DEVELOPMENT AND LOCAL PROTECTIVE MECHANISMS

Belov G.V.1,2, Zakirova T.A.1, Talantbekova N. T.2

Abstract
Introduction. In the tobacco-growing farms of Kyrgyzstan, work with green leaves and dried tobacco raw materials is mostly done on home plots by women of reproductive age. Children of middle and high schools are attracted to the production. Preschoolers and junior schoolchildren are for a long time with mothers employed in production. 
The work was aimed at assessing the physical development and state of the local protective mechanisms of the respiratory system in 100 children living in the tobacco farms of the Osh region. The comparison group consisted of 100 children of the same age living in horticultural and vegetable farms of the same districts.
The results of the study indicate a higher frequency of allergic rhinitis and atopic dermatitis in the main group, their lag in physical development and a decrease in the protective mechanisms of the respiratory and immune system. Activation of lipid peroxidation and a decrease in the surface activity of nasal swabs and exhaled air condensate, an increase in neutrophils and eosinophils in smears of the nasal mucosa, an increase in serum IgM, IgG d were detected. 
Recommendation. This testifies to the effect of tobacco on children during processing and storing it in local areas.
Key words: green tobacco disease, nicotine, children, physical development, surfactant, peroxidation, immunoglobulin